This article is one of the better ones I have read on how to prepare to ride to Prudhoe Bay.
Really know how to use your First Aid kit and have a decent sized one the thou have supplemented to better manage a serious MC get off.
Strip your bike of everything you don't need to keep you alive and the bike running and leave it in your Motel's storage in Fairbanks.
Carry a gallon of water each above what you normally would carry.
Sat Phone & Spot Yes
Run Knobbies - 100% Yes. If you are bring to economize on tires or don't think they are necessary you will be having losts of chances to reflect on the error of your ways.
If you are caring spare tires wrap them in the clear plastic shrink wrap tape so if you have to change one out it is still clean inside.
Side note. While riding to Prudhoe gets all the press those of us who have ridden to both Prudhoe and Inuvik for the most part rank the ride to Inuvik as much more difficult.
1. More remote. There is a reason they have emergency air tips along the road.
2. Far Less traffic
3. Road conditions are worse for longer. We had construction for 1/3 of the way
4. With Klondike River Crossing burned getting to and from Eagle Plains is more of a gas challenge.
The Dempster is a clay based road and as such the bottoms of hills can be very, very nasty.
Take a bug hat and a survival blanket.
Always assume that 10 KMs from the next gas station there could be a rock/mud slide and you need to think ahead regarding how you are getting back with enough gas.
Carry tie down straps and lots of cash so you can put a damaged bike on a truck.
Buy the BCAA Platinum Coverage to avoid the big tow bill.
DOn't hurry on the road. Speed kills up there
You need a GPS so you can tell people where you are if you need help. A waypoint lets the rescue tow truck people know where you are.
Read AKrider's mile by mile report (with photos) on the Dalton on adv rider.
Try to ride in a group of three bikes.
One to crash , one to stay with injured rider, one to ride for help
How remote is it? Here is a Photo of my my wife and riding buddy riding north.heading North after Eagle Plains when the road was perfect.