I just bought an 07 DRZ400S. Great comprimise bike. I came from a DL650 and tried the DR650. Was not impressed. The 650 bikes have changed very little in their technology. Except for the Husky TE610 (aftermarket stuff is still needed), XR650R weak subframe, these are the comparable bikes.
After 2000 the DRZ was up grade with better forks. I've been happy with the DRZ and it fits in well for the varied riding I want to do. With stock gearing its not bad on the Hwy, 120km/h and the motor does not seem to be reving extremely high. Good off road if you can ride a bike, a lttle weighty when it starts to go down. Excellent small dual sport bike, you can load it up and the sub frame will handle it. After market stuff is readily available, although if you go larger then a ie. Clarke tank you will have to modify things. I'd recommend it as a comprimise bike. Does most things well.